Bench To Bedside

Bench to Bedside Outline A. What is work judicatory to bedside look for? * Described as test and error process where physician researchers find vernal research in the laboratory and then do clinical streamlets on patients * Most of these patients be not tenders ab initio; researchers unremarkably tests on animals first before injecting the dose into human patients B. What argon some types of bench to bedside research? * Basic research- they decompose jail cell structure of cells and try to determine whether they atomic number 18 cancer cells or not. If they find some strange they disperse it to * Preclinical- is the actual work that is through in the lab. There are two types of preclinical research called in vitro and in vivo. * In vitro means in glass; tests using cell lines and/or cell cultures contained in petri dishes and test tubes * In vivo means trial with push through glass; testing on animals and collect informatio n active the activity of the drug ( cognise as pharmocodynamic testing), as salutary as absorption, distri simplyion, excretion known as (pharmacokinetic testing) and toxicity. C. What are the trials of bench to bedside research? * bod 1- judge the drugs and do research. Find out what dose of the drug is uninjured and how it should be given.

* Phase 2- the trial and error part; appreciate the drug and take denary Is the drug effective? Does it fill further testing? go under the dose if these questions have been answered. * Phase 3- Tie the research together. relish at predicted results and final results. rate the efficiency toward the standard of care. ! whence confirm or deny the dose. D. What are some examples of bench to bedside research being done? * One of the first examples that was use for bench to bedside research was Anti-angiogensis * Folkman who make his idea in 1971, but it wasnt until 2002 that Avastin, the VEGF inhibitior was approved for treating colon cancer * UGA researchers actually plunge a new treatment for...If you deficiency to get a full essay, order it on our website: BestEssayCheap.com

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